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Outcomes tend to be better when they are used as part of a broader plan that includes adequate nutrition and ongoing support

I would not be surprised if SUD eventually became a clinical indication for using a GLP-1. Lacking that, DeRoo said that the ideal patients who can benefit from GLP-1 off-label uses across mental health are those who already meet clinical criteria to receive a prescription for a GLP-1

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In addition, because the demonstration will operate outside the Part D benefit, the manufacturers wont be responsible for providing the manufacturer price discount on eligible GLP-1s (10% in the Part D initial benefit phase and 20% in the catastrophic phase.) While many prior section 402 demonstrations have had to conform to budget neutrality rules by the Office of Management and Budget (OMB), some demonstrations have been able to move forward without this requirement

J Hepatol 2021;75:795-809